OECD Principles For The Validation, For Regulatory Purposes, Of (Quantitative) Structure-Activity Relationship Models
Tuesday, December 16th, 2008In 2004, OECD came up with 5 principles for QSAR models. They are:
- a defined endpoint
- an unambiguous algorithm
- a defined domain of applicability
- appropriate measures of goodness-of– fit, robustness and predictivity
- a mechanistic interpretation, if possible
If you are working on QSAR models, it will be good for you to know these principles and apply them in your work.
For more information on these principles, you can go to the OECD website
